Endocrine Abstracts

Adrenocortical carcinoma (ACC) is an aggressive cancer, with, in its advanced stages, a median 5-year survival rate of less than 15%. ACC is rare in humans, but in dogs the incidence is at least 100 times higher. Because these dogs receive medical care, have an intact immune system, and have inter-individual and intratumoral heterogeneity, the dog is a unique spontaneous animal model to study new treatment options for ACC. However, to determine similarity of canine and human A...